Synergistic Effect of miR-383 and Cisplatin on Inhibition of Growth, Proliferation, and Migration of Lung Cancer Cells
The findings indicate that the combination treatment of miR-383 and cisplatin suppressed cell proliferation, migration and colony formation while enhancing the sensitivity of A549 cells to chemotherapy compared to monotherapy. These results suggest that miR-383 combination therapy warrants further investigation as a potential strategy for LC treatment.
Authors
- Behzad Baradaran (ORCID: https://orcid.org/0000-0002-8642-6795)
- Asiyeh Jebelli (ORCID: https://orcid.org/0000-0001-9494-2207)
- Ahad Mokhtarzadeh (ORCID: https://orcid.org/0000-0002-4515-8675)
- Maryam Tohidast (ORCID: https://orcid.org/0000-0003-4673-554X)
- Seyed Samad Hosseini (ORCID: https://orcid.org/0000-0002-3722-4716)
- Mohammad Amini (ORCID: https://orcid.org/0000-0001-7543-9577)
- Vagef Elyaszadeh (ORCID: https://orcid.org/0009-0003-8817-7109)
- Parinaz Marami (ORCID: https://orcid.org/0009-0006-9115-1729)
Institutions
- Tabriz University of Medical Sciences (IR)
- Kharazmi University (IR)
- Sadra Institute Of Higher Education (IR)
Publication Details
- Journal
- Archives of Iranian Medicine
- Published
- 2025-05-01
- DOI
- https://doi.org/10.34172/aim.33450
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00