Suppression of the antioxidation process by iron ions (II)

Antioxidant system of malignant cells interferes with cancer chemotherapy. The influence of pyrocatechol on the oxidation of propanol-2 by atmospheric oxygen during the radiolysis of its 1 M aqueous solutions was studied. Adding 0.01 M pyrocatechol to the solution reduced the intensity of oxidation and the formation of acetone. The yield of acetone increased with the joint presence of pyrocatechol and iron ions in solution. It has been shown that Fe 2+ ions can suppress the antioxidant effect of the diphenolic antioxidant pyrocatechol.