Evaluation of Tissue Expression of HMBG1 protein in Patients With Breast Cancer

The proportion of breast cancer patients with HMGB1 expression was lower in the present study than that reported previously. Furthermore, we did not detect a relationship between HMGB1 expression and prognosis. However, the relationship between HMGB1 expression and prognosis had been previously reported only in aggressive breast cancers. It is suggested that understanding the significance of HMGB1 expression in breast cancer may open new treatment opportunities, especially in aggressive and/or triple negative tumors.

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Journal
European Journal of Breast Health
Published
2025-05-29
DOI
https://doi.org/10.4274/ejbh.galenos.2025.2025-4-2
Primary Topic
Metabolism, Diabetes, and Cancer
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article
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article

Evaluation of Tissue Expression of HMBG1 protein in Patients With Breast Cancer

Duygu Ayaz, Gülden Dınız, Umut Varol, Dudu Solakoğlu Kahraman et al.
1 links
European Journal of Breast Health
Metabolism, Diabetes, and Cancer
article

Evaluation of Tissue Expression of HMBG1 protein in Patients With Breast Cancer

Duygu Ayaz, Gülden Dınız, Umut Varol, Dudu Solakoğlu Kahraman, İsmail Güzeliş, Mustafa Değirmenci
article en

Abstract

The proportion of breast cancer patients with HMGB1 expression was lower in the present study than that reported previously. Furthermore, we did not detect a relationship between HMGB1 expression and prognosis. However, the relationship between HMGB1 expression and prognosis had been previously reported only in aggressive breast cancers. It is suggested that understanding the significance of HMGB1 expression in breast cancer may open new treatment opportunities, especially in aggressive and/or triple negative tumors.

European Journal of Breast HealthVol. 21(4)
Izmir University (TR), Sağlık Bilimleri Üniversitesi (TR), Izmir Tepecik Eğitim ve Araştırma Hastanesi (TR)
Good health and well-being
Openalex Percentile: Top 89%
Metabolism, Diabetes, and Cancer
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Evaluation of Tissue Expression of HMBG1 protein in Patients With Breast Cancer — Duygu Ayaz, Gülden Dınız, et al. · European Journal of Breast Health (2025) | TGRS Research Map | TGRS