A population pharmacokinetic approach to compare 51Cr-EDTA and 99 mTc-DTPA clearances in measuring renal glomerular filtration rate in oncopediatrics
This result confirmed that both radioisotopic clearances are equivalent in pediatrics, as has been reported in the literature on adults based on intrapatient comparisons. The value of the population approach in comparing the pharmacokinetics of two different compounds is thus demonstrated.
Authors
- Étienne Chatelut (ORCID: https://orcid.org/0000-0002-7740-9096)
- Mathieu Alonso
- Marlène Pasquet (ORCID: https://orcid.org/0000-0001-6919-8383)
- Matthieu Gracia (ORCID: https://orcid.org/0009-0006-9960-8156)
- Victoire Ankaoua
Institutions
- École Nationale de l’Aviation Civile (FR)
- Inserm (FR)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Centre de Recherches en Cancérologie de Toulouse (FR)
- Institut universitaire du cancer de Toulouse Oncopole (FR)
- Institut Claudius Regaud (FR)
Publication Details
- Journal
- Pediatric Nephrology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1007/s00467-025-06828-9
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Université de Toulouse