Data-Driven, AI-Computed Personalized Nutrition Platform – Towards Prevention of Chronic Diseases and Cancers

levels; p 0.01 for time to peak) followed by a plasma melatonin plateau over the night and tapering off from 6 hours.AUC analysis across 8 hours showed MLT increased plasma melatonin more than placebo (p < 0.001).In the SQ study, MLT reduced sleep latency by 43% compared to PLA (ANCOVA: F 4.6, p < 0.05) and improved deep sleep 1.5-3 hours and light sleep 6+ hours into sleep (both p < 0.05).92% of subjects reported waking up fresh and rested more often after MLT compared to 50% after PLA (WHO-5, Bernard's exact test p < 0.05), with no rebound effect after discontinuation.Conclusions: MLT improved sleep latency and sleep architecture indicative of a better natural sleep-wake cycle.MLT may be considered an effective supplement to improve parameters of sleep quality among adults with poor sleep, without withdrawal concerns.