From Sanger to Oxford Nanopore MinION Technology: The Impact of Third-Generation Sequencing on Genetic Hematological Diagnosis
With a 99.43% concordance observed in our comparison, our results support the implementation of MinION technology in routine variant detection in MPN, MDS, AML, and CML cases due to its significant advantages over Sanger sequencing.
Authors
- Felipe Prósper (ORCID: https://orcid.org/0000-0001-6115-8790)
- Irache Erdozain
- J. Rifón (ORCID: https://orcid.org/0000-0002-1649-8478)
- Ana Alfonso Piérola (ORCID: https://orcid.org/0000-0002-2478-5354)
- María José Larráyoz (ORCID: https://orcid.org/0000-0003-0667-1959)
- Ada Esteban-Figuerola (ORCID: https://orcid.org/0000-0002-4590-0999)
- Diego Robles de Castro (ORCID: https://orcid.org/0000-0002-4411-104X)
- María García‐Fortes (ORCID: https://orcid.org/0000-0002-0959-9449)
- Marı́a José Calasanz (ORCID: https://orcid.org/0000-0002-0374-3008)
- Oihane Churruca
- Pablo Luri-Martin (ORCID: https://orcid.org/0009-0004-5604-0594)
- Carlos de Miguel
- Beñat Ariceta (ORCID: https://orcid.org/0000-0001-8819-402X)
- Amagoia Mañú
- Natalia Gordillo
Institutions
- Hospital Txagorritxu (ES)
- Navarre Institute of Health Research (ES)
- Clinica Universidad de Navarra (ES)
- Hospital San Pedro (ES)
- Hospital Clínico Universitario Virgen de la Victoria (ES)
- Centro de Investigación Biomédica en Red de Cáncer (ES)
- Universidad de Navarra (ES)
Publication Details
- Journal
- Cancers
- Published
- 2025-05-29
- DOI
- https://doi.org/10.3390/cancers17111811
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad de Navarra