Study Protocol Abstract: The Effect of Regular Lentil and Chickpea Intake on Gut Microbiome and Metabolic Health in Healthy Young Adults: A Pilot Randomized Clinical Trial
of endothelial function (flow-mediated dilation), and arterial stiffness (pulse-wave analysis and velocity), 3-day food logs, and questionnaires (to assess subjective stress and anxiety levels, activity, sleep quality, and gastrointestinal symptoms).Results: The study is currently ongoing.Upon abstract submission, 56 participants have been screened for eligibility and 13 have been enrolled (37 excluded due to low BMI, 2 excluded for gluten allergy, 3 excluded outside age range, and 1 excluded for recent antibiotic use).Conclusions: To our knowledge, this will be the first study to examine the impact of fresh daily watermelon consumption on gut microbiome, metabolome, and intestinal health features in a clinical cohort.
Authors
- Gloria Salazar (ORCID: https://orcid.org/0000-0002-6239-7942)
- Ravinder Nagpal (ORCID: https://orcid.org/0000-0002-4250-1749)
- Saiful Singar (ORCID: https://orcid.org/0000-0002-3138-6634)
- Joseph C. Watso (ORCID: https://orcid.org/0000-0001-7840-0643)
- Cole Patoine
Institutions
- Florida State University (US)
Publication Details
- Journal
- Current Developments in Nutrition
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.cdnut.2025.107359
- Primary Topic
- Nutrition, Genetics, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- National Institutes of Health