What Is “Healthy” Food? Evaluating Foods and Beverages Consumed by US Adults That Satisfy the US Food and Drug Administration’s Updated “Healthy” Claim Criteria
create a database on amino acid oro-ileal digestibility for protein quality scoring of human foods.Methods: The 2022 FAO/IAEA Technical Meeting recommended the collection of protein and amino acids oro-ileal digestibility data obtained in vivo in humans, pigs and rats.A systematic review was carried out using bibliographic databases (Scopus, Web of Science, PubMed Central) to end of November 2024.An FAO/IAEA technical advisory group was held in March 2024, and an expert meeting held in November 2024 to guide the database construction and architecture and define the inclusion criteria.Results: A total of 5,313 published articles were identified, of which 1,088 were eligible after title and abstract screening, and a final ~550 full text articles were included for data extraction.The database included food description (name, food group, origin, seasonality, processing etc.), protein and amino acid content (per 100g food and per g of protein), moisture content, protein and amino acid ileal digestibility, and ileal score calculations (ileal-PDCAAS, DIAAS) by age groups.Data on the metabolic availability of amino acids, measured by indicator amino acid oxidation (IAAO), were separately included, considering that they are a different measurement.Conclusions: The literature is sufficiently advanced to support a database on ileal digestibility of amino acids in human foods.Standardised protocols should be used, animal data should be validated against human data, and in the future in vitro data could be included after validation.A final goal of the database is to help in the development of dietary guidelines to best ensure the protein needs of human populations.
Authors
- Julia A. Wolfson (ORCID: https://orcid.org/0000-0001-9155-2609)
- Anna Claire Tucker (ORCID: https://orcid.org/0000-0002-1433-3717)
- Laura E. Caulfield (ORCID: https://orcid.org/0000-0001-7152-1004)
- Casey M. Rebholz (ORCID: https://orcid.org/0000-0002-5442-8745)
Institutions
- Johns Hopkins University (US)
Publication Details
- Journal
- Current Developments in Nutrition
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.cdnut.2025.107292
- Primary Topic
- Consumer Attitudes and Food Labeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Heart, Lung, and Blood Institute