Longitudinal analysis of step counts in Parkinson’s disease patients: insights from a web-based application and generalized additive model

Based on the PPMI data, we find that sex, handedness, PD status of father, COVID-19 status, cohort, and the smoothing functions of age are all statistically significant for step counts. Additionally, a web application tailored specifically for step count analysis in PD patients was developed. This tool provides a user-friendly interface for patients, caregivers, and healthcare professionals to track and analyze step count data, facilitating personalized treatment plans and enhancing the management of PD.