LETM-Domain Containing 1 (LETMD1) Enhances Energy Expenditure in Human Beige Adipocytes
in Asian women (26.50) and Asian men (27.32).These differences may be influenced by unmeasured confounders like occupational types, dietary habits, and physiology.Groups at higher risk of BMI increase under overworking ( >60 hours) include Asian American men (1.08), Asian American women (1.30), multiracial men (1.33), multiracial women (0.93), and White women (1.03).Conclusions: Due to computational constraints, we reduced the training set size, which affected model precision and increased sensitivity to outliers.BMI, developed using data from primarily white men, lacks accuracy across different racial, ethnic, and gender groups.It also fails to account for fat distribution and muscle mass, misclassifying muscular individuals as overweight.
Authors
- Xiaoyan Hui (ORCID: https://orcid.org/0000-0002-7525-5812)
- Donghai Wu (ORCID: https://orcid.org/0000-0002-4638-3743)
- Jiaxin Liu (ORCID: https://orcid.org/0000-0001-9204-3988)
- Wei Sun (ORCID: https://orcid.org/0000-0002-8807-1801)
- Shiqing Liang (ORCID: https://orcid.org/0000-0001-7428-1456)
Institutions
- Chinese University of Hong Kong (HK)
- Guangzhou Institutes of Biomedicine and Health (CN)
Publication Details
- Journal
- Current Developments in Nutrition
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.cdnut.2025.107265
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00