Left Heart Abnormalities in Patients With Lung Disease, OSA, and Chronic Thromboemboli at Risk for or With Known Pulmonary Hypertension
Quantifying pretest probability for HFpEF in patients with sleep apnea, lung disease, or chronic thromboemboli identifies a progressive gradient for dynamic PCWP abnormalities with worse functional status and quality of life. These subclinical left heart abnormalities are not universally detectable by resting right heart catheterization alone and call for further study of whether strategies to prevent or treat HFpEF might improve functional status in these patients with high risk of occult HFpEF.
Authors
- J. Emanuel Finet (ORCID: https://orcid.org/0000-0002-0156-6757)
- Paul M. Hassoun (ORCID: https://orcid.org/0000-0003-0601-4975)
- Serpil C. Erzurum (ORCID: https://orcid.org/0000-0001-5202-9065)
- Barry A. Borlaug (ORCID: https://orcid.org/0000-0001-9375-0596)
- Yogesh N.V. Reddy (ORCID: https://orcid.org/0000-0001-5322-0902)
- Stephen C. Mathai (ORCID: https://orcid.org/0000-0003-3188-7209)
- W.H. Wilson Tang (ORCID: https://orcid.org/0000-0002-8335-735X)
- Christine Jellis (ORCID: https://orcid.org/0000-0002-8610-0533)
- Evelyn M. Horn (ORCID: https://orcid.org/0000-0002-5751-9415)
- Anna R. Hemnes (ORCID: https://orcid.org/0000-0002-2755-5845)
- Jane A. Leopold (ORCID: https://orcid.org/0000-0003-0598-8882)
- Franz Rischard (ORCID: https://orcid.org/0000-0002-6861-8304)
- Nicholas S. Hill (ORCID: https://orcid.org/0000-0002-8242-8339)
- Robert P. Frantz (ORCID: https://orcid.org/0000-0003-4128-3978)
- Erika B. Rosenzweig (ORCID: https://orcid.org/0000-0003-4849-214X)
- Reena Mehra (ORCID: https://orcid.org/0000-0002-6222-2675)
- Gerald J. Beck (ORCID: https://orcid.org/0000-0002-8876-5045)
Institutions
- Brigham and Women's Hospital (US)
- Tufts Medical Center (US)
- Cleveland Clinic (US)
- Mayo Clinic (US)
- Johns Hopkins University (US)
- University of Washington (US)
- Cornell University (US)
- Johns Hopkins Medicine (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Maria Fareri Children's Hospital (US)
- Pulmonary and Allergy Associates (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
- Pulmonary and Critical Care Associates (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Circulation Heart Failure
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1161/circheartfailure.125.012912
- Citations
- 5
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.59