Single-cell RNA sequencing reveals the role of GTF2F2 in ovarian cancer oncogenesis and progression
The risk score model established in this study offers a novel framework for patient stratification and personalized therapy. Notably, the identification of the UBE2C + Epi subpopulation and key genes such as GTF2F2 highlights potential diagnostic and therapeutic targets, shedding light on the pathogenesis of ovarian cancer and paving the way for precision medicine approaches.
Authors
- Xuejie Song (ORCID: https://orcid.org/0009-0009-1325-1793)
- Fuchun Si (ORCID: https://orcid.org/0000-0002-9880-7333)
- Gao Si (ORCID: https://orcid.org/0000-0002-9583-1928)
- Jiqing Si
- Haiyang Du
Institutions
- Henan University of Traditional Chinese Medicine (CN)
- Peking University (CN)
- Peking University Third Hospital (CN)
- First Affiliated Hospital of Henan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1186/s13048-025-01686-3
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81