The Predictive Value of Systemic Immune Inflammatory Index for the Occurrence and Development of Coronary Heart Disease

冠心病(Coronary Artery Disease, CAD)是全世界范围内发病率和死亡率均居首位的心血管疾病。近年来，冠心病的疾病负担在全球范围内显著上升，严重影响着人类的健康。冠心病其本质是一种炎症性疾病，许多炎症标志物被报道与冠心病有关。据国内外相关研究，免疫反应在冠心病的发生发展过程中也发挥着必不可少的作用。全身免疫炎症指数(Systemic Immune Inflammation Index, SII)能反映机体炎症及免疫状态的一个新型炎症指标，多项研究表明其可能与冠心病的发生、发展及预后密切相关。本文旨在从SII在预测冠心病发生发展中的价值，以及其在引发冠心病中的作用机制着手，为SII在未来冠心病的预防和治疗中提供理论支持。Coronary Artery Disease (CAD) is the cardiovascular disease with the highest incidence rate and mortality in the world. In recent years, the disease burden of coronary heart disease has significantly increased globally, seriously affecting human health. Coronary heart disease is essentially an inflammatory disease, and many inflammatory markers have been reported to be associated with coronary heart disease. According to relevant research at home and abroad, immune response also plays an essential role in the occurrence and development of coronary heart disease. The Systemic Immune Inflammation Index (SII) is a novel inflammatory indicator that reflects the inflammatory and immune status of the body. Multiple studies have shown that it may be closely related to the occurrence, development, and prognosis of coronary heart disease. This article aims to provide theoretical support for the future prevention and treatment of coronary heart disease by starting from the value of SII in predicting the occurrence and development of coronary heart disease, as well as its mechanism of action in triggering coronary heart disease.