Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression
These findings suggest that tumor-derived exosomal SLC12A2-DT facilitates HCC progression by modulating the interplay between HCC cells and TAMs through the Wnt/GSK3β/β-catenin signaling pathway.
Authors
- Di Ma (ORCID: https://orcid.org/0000-0002-7051-7393)
- Jingyi Zhou (ORCID: https://orcid.org/0000-0002-6860-6469)
- Fan Wang (ORCID: https://orcid.org/0000-0002-9869-9504)
- Ling Xu
- Chuan Liu
- Chen Wang (ORCID: https://orcid.org/0000-0001-6461-1271)
- Qi Li (ORCID: https://orcid.org/0000-0003-2588-6541)
- Yuan Lin (ORCID: https://orcid.org/0000-0001-5449-3435)
- Wencong Ma (ORCID: https://orcid.org/0000-0001-9236-129X)
- Ruixin Zhou (ORCID: https://orcid.org/0000-0001-7985-5260)
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Tongren Hospital (CN)
- Shanghai East Hospital (CN)
- Shanghai First People's Hospital (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1016/j.intimp.2025.114955
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China