Targeting AGE-RAGE Signaling Pathway with Hujin Decoction Ameliorates MAFLD in HepG2 Cells
HJD may act on RAGE, BCL2, CASP3, and other key targets to regulate the AGE-RAGE signaling pathway through succinic acid, Ginsenoside Rh4 and Caffeic acid. This study provides a theoretical basis for the clinical application and quality control of HJD.
Authors
- Jiaxi Shi (ORCID: https://orcid.org/0009-0001-8428-4738)
- Fuxuan Liu
- Zixuan Zhang (ORCID: https://orcid.org/0000-0002-6932-5941)
- Xuguang Shi (ORCID: https://orcid.org/0000-0003-2437-6400)
- Jing Zhou (ORCID: https://orcid.org/0000-0001-7768-8315)
- Qi Shen
Institutions
- Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- Diabetes Metabolic Syndrome and Obesity
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/dmso.s506350
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00