Proteomic Landscape of Small Extracellular Vesicles Derived From Gastric Juice and Identified TFF2 as a Specific Biomarker
The UC method is suitable for isolating gsEVs, particularly for mass spectrometry-based proteomic analysis. The small peptide TFF2 may serve as a potential specific biomarker for gsEVs. This study offers new insights for research on sEVs in gastric diseases.
Authors
- Ruiling Fan
- Kaiwen Wu (ORCID: https://orcid.org/0000-0001-5289-4024)
- Wenqi Luo (ORCID: https://orcid.org/0000-0003-3881-2357)
- Lüye Liu
- Bin Yuan (ORCID: https://orcid.org/0000-0003-0288-1879)
- Jingwei Yang (ORCID: https://orcid.org/0000-0002-3553-5027)
- Liu Liu (ORCID: https://orcid.org/0000-0001-6737-5999)
- Chunyang Zhou (ORCID: https://orcid.org/0000-0001-9946-6158)
- Yueshan Sun
- Lei Liu (ORCID: https://orcid.org/0000-0001-5309-1979)
- Xiaobin Sun
- Yuanbiao Guo (ORCID: https://orcid.org/0000-0002-7571-8864)
- Yu Liu (ORCID: https://orcid.org/0000-0002-3108-9947)
- Tao Jiang (ORCID: https://orcid.org/0000-0001-8835-2905)
- Binjun Zhu
Institutions
- North Sichuan Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Third People's Hospital of Chengdu (CN)
- Fourth People's Hospital of Sichuan Province (CN)
- Deyang Stomatological Hospital (CN)
- Shanghai Pulmonary Hospital (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/ijn.s516605
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61