Dual targeted Ugi-bisamides induce caspase-mediated apoptosis and inhibit PI3K/mTOR signaling in NSCLC
Ugi adduct 8 exhibited potent anti-cancer against NSCLC cancer cells though caspase-mediated apoptosis and PI3K/mTOR inhibition signaling pathway.
Authors
- Marwa F. Harras (ORCID: https://orcid.org/0000-0003-4723-6179)
- Mohamed S. Nafie (ORCID: https://orcid.org/0000-0003-4454-6390)
- Magda M. F. Ismail (ORCID: https://orcid.org/0000-0002-3915-9786)
- Gina N. Tageldin (ORCID: https://orcid.org/0000-0002-4048-3604)
- Aliaa A. Masoud
- Hamida Abdel‐Hamid (ORCID: https://orcid.org/0000-0002-0212-3157)
- Doaa Ahmad Ghareeb (ORCID: https://orcid.org/0000-0003-3327-4377)
- Mohammed Salah Ayoup (ORCID: https://orcid.org/0000-0001-6715-5478)
- Jawaher Y. Al Nawah (ORCID: https://orcid.org/0009-0002-8617-9445)
- Khadiga Yousry
Institutions
- Suez Canal University (EG)
- Pharos University in Alexandria (EG)
- Al-Azhar University (EG)
- University of Sharjah (AE)
- City of Scientific Research and Technological Applications (EG)
- King Faisal University (SA)
- Alexandria University (EG)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj00670h
- Citations
- 2
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.61