Role of HMGB1 on the onset of preeclampsia
This study identifies significantly increased HMGB1 placental expression predominantly in EO-PE, supporting its role in heightened inflammation and endothelial dysfunction characteristic of this subgroup, suggesting its potential as a biomarker and therapeutic target specifically for EO-PE.
Authors
- Fırat Aşir (ORCID: https://orcid.org/0000-0002-6384-9146)
- Nizamettin Bozbay (ORCID: https://orcid.org/0000-0001-9632-5093)
- Ayşegül Aşır (ORCID: https://orcid.org/0000-0001-9056-144X)
- Mehmet Yılmaz
- İbrahim Batmaz (ORCID: https://orcid.org/0000-0001-9492-2783)
- Fatih Taş (ORCID: https://orcid.org/0000-0001-9817-4241)
- Tuğcan Korak (ORCID: https://orcid.org/0000-0003-4902-4022)
- Fikri Erdemci (ORCID: https://orcid.org/0000-0001-8083-0183)
Institutions
- Dicle University (TR)
- Selçuk University (TR)
- Siirt Üniversitesi (TR)
- Dokuz Eylül University (TR)
- Bandırma Onyedi Eylül University (TR)
- Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi (TR)
- Kocaeli Üniversitesi (TR)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1186/s12884-025-07701-1
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00