Identification of esophageal cancer tumor antigens and immune subtypes for guiding vaccine development
In our analysis, <i>BTN2A1</i>, <i>MICA</i>, and <i>HHLA2</i> displayed significant potential as antigens for the development of anti-ESCA messenger RNA (mRNA) vaccines. The identification of three stable and reproducible immune subtypes specific to ESCA may prove essential in predicting the outcome of mRNA vaccines.
Authors
- Hongmei Gu (ORCID: https://orcid.org/0000-0002-8572-5435)
- Xiaodong Xu (ORCID: https://orcid.org/0000-0002-5290-9705)
- Qiang Xue (ORCID: https://orcid.org/0000-0002-9586-704X)
- Ruiqi Liu (ORCID: https://orcid.org/0000-0002-2099-620X)
- Yanrong Chen (ORCID: https://orcid.org/0000-0002-6441-3459)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2025-05-01
- DOI
- https://doi.org/10.21037/jtd-2025-233
- Citations
- 1
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.80