Association of Demographic Variables with Senile Cataract: A Cross Sectional Study

Background: Senile cataracts remain a leading cause of avoidable blindness worldwide, especially among the elderly. Understanding the interplay of socio-demographic, environmental, and systemic health variables can aid in effective prevention strategies. Objective: To identify and evaluate key risk factors associated with senile cataract development in a diverse adult population aged 50 years and above. Methods: A population-based cross-sectional study was conducted among 11,523 individuals from both urban and rural settings. Participants were stratified by region, and risk factors including age, gender, socio-economic status, occupation, addiction history, and systemic comorbidities were analyzed. Cataract status was clinically confirmed. Logistic regression analyses were used to determine associations between variables and cataract development. Results: Cataract prevalence increased significantly with age, especially after 60 years. Male gender (Adjusted OR: 2.71, 95% CI: 2.38–3.08), rural residence (Adjusted OR: 2.16, 95% CI: 1.92–2.44), and outdoor occupation (Adjusted OR: 1.89, 95% CI: 1.65–2.17) were independently associated with cataract. Lower socio-economic status (Adjusted OR: 1.67, 95% CI: 1.45–1.91), diabetes mellitus (Adjusted OR: 1.92, 95% CI: 1.59–2.32), and hypertension (Adjusted OR: 2.44, 95% CI: 1.91–3.12) were also significant risk factors. Addiction (including smokeless tobacco) was not an independent predictor after adjusting for confounders. Conclusion: This study highlights the multifactorial nature of senile cataract development, with age, male gender, rural residence, low socio-economic status, systemic diseases, and occupational UV exposure as major contributors. These findings support the need for tailored public health interventions targeting vulnerable populations.

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Publication Details

Journal
Ophthalmology Research An International Journal
Published
2025-05-29
DOI
https://doi.org/10.9734/or/2025/v20i3458
Primary Topic
Connexins and lens biology
Type
article
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article

Association of Demographic Variables with Senile Cataract: A Cross Sectional Study

Ragni Kumari
Ophthalmology Research An International Journal
Connexins and lens biology
article

Association of Demographic Variables with Senile Cataract: A Cross Sectional Study

Ragni Kumari
article en

Abstract

Background: Senile cataracts remain a leading cause of avoidable blindness worldwide, especially among the elderly. Understanding the interplay of socio-demographic, environmental, and systemic health variables can aid in effective prevention strategies. Objective: To identify and evaluate key risk factors associated with senile cataract development in a diverse adult population aged 50 years and above. Methods: A population-based cross-sectional study was conducted among 11,523 individuals from both urban and rural settings. Participants were stratified by region, and risk factors including age, gender, socio-economic status, occupation, addiction history, and systemic comorbidities were analyzed. Cataract status was clinically confirmed. Logistic regression analyses were used to determine associations between variables and cataract development. Results: Cataract prevalence increased significantly with age, especially after 60 years. Male gender (Adjusted OR: 2.71, 95% CI: 2.38–3.08), rural residence (Adjusted OR: 2.16, 95% CI: 1.92–2.44), and outdoor occupation (Adjusted OR: 1.89, 95% CI: 1.65–2.17) were independently associated with cataract. Lower socio-economic status (Adjusted OR: 1.67, 95% CI: 1.45–1.91), diabetes mellitus (Adjusted OR: 1.92, 95% CI: 1.59–2.32), and hypertension (Adjusted OR: 2.44, 95% CI: 1.91–3.12) were also significant risk factors. Addiction (including smokeless tobacco) was not an independent predictor after adjusting for confounders. Conclusion: This study highlights the multifactorial nature of senile cataract development, with age, male gender, rural residence, low socio-economic status, systemic diseases, and occupational UV exposure as major contributors. These findings support the need for tailored public health interventions targeting vulnerable populations.

Ophthalmology Research An International JournalVol. 20(3)
Openalex Percentile: Top 89%
Connexins and lens biology
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