Critical role of spread through air spaces in prognosis of stage IA3 non-small cell lung cancer: insights from a real-world multicenter study
The cell nest STAS subtype, tumor-stroma ratio, and smoking history are independent prognostic factors influencing PFS and OS in stage IA3 NSCLC. These findings underscore the need for detailed assessments of STAS subtypes and histopathological heterogeneity to refine prognostic evaluations and optimize clinical decision-making.
Authors
- Guofeng Yang (ORCID: https://orcid.org/0000-0002-9713-5846)
- Guibin Huang (ORCID: https://orcid.org/0000-0003-3286-6194)
- Shaobin Yu (ORCID: https://orcid.org/0000-0001-7074-7458)
- Shuchen Chen (ORCID: https://orcid.org/0000-0002-3316-9908)
- Z. Zhang (ORCID: https://orcid.org/0009-0009-7650-353X)
- Hui Chen (ORCID: https://orcid.org/0000-0001-6883-3752)
- Xiao Han (ORCID: https://orcid.org/0000-0003-3787-3529)
Institutions
- Fujian Medical University (CN)
- Ningde Normal University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2025-05-01
- DOI
- https://doi.org/10.21037/jtd-2024-2209
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00