Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population (Adv. Sci. 20/2025)
Gut Microbiota‐Butyrate‐PPARγ This study demonstrates that gut microbiota‐derived butyrate promotes adipose ST2(+) regulatory T cell population through PPARγ activation. The cover illustration depicts gut microbiota (represented by orange‐shaped bacterial cells) releasing butyrate (represented as blue particles and blue molecular structures), which transmit electrical‐like signals to activate ST2(+) regulatory T cells (shown in purple) in adipose tissue (orange cells), highlighting their role in maintaining adipose tissue immune homeostasis. More details can be found in article number 2411086 by Weiqing Wang, Ruixin Liu, and co‐workers. Cover design by Rui Xie. [Image: see text]
Authors
- Zhiwen Cao
- Minchun Zhang
- Yufang Bi (ORCID: https://orcid.org/0000-0002-9536-2682)
- Lizhi Guan (ORCID: https://orcid.org/0000-0002-5502-8444)
- Yunqi Li (ORCID: https://orcid.org/0000-0002-5190-3037)
- Lei Wu (ORCID: https://orcid.org/0000-0002-8556-0343)
- Ruixin Liu (ORCID: https://orcid.org/0000-0002-5526-6717)
- Chao Wu (ORCID: https://orcid.org/0000-0002-8417-7043)
- Jiqiu Wang (ORCID: https://orcid.org/0000-0002-9383-7656)
- Banru Chen (ORCID: https://orcid.org/0009-0003-9478-1329)
- Bin Li (ORCID: https://orcid.org/0000-0003-1692-8957)
- Weiqing Wang (ORCID: https://orcid.org/0000-0001-6027-3084)
- Yufei Chen
- Yiwen Gong
- Guang Ning (ORCID: https://orcid.org/0000-0002-9728-2897)
- Chengcan Yang (ORCID: https://orcid.org/0000-0002-4211-9478)
- Bing Wang
Publication Details
- Journal
- Advanced Science
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1002/advs.202570151
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00