Safety and Efficacy of Dapagliflozin in Patients With Systemic Right Ventricular Dysfunction: DAPA‐SRVTrial

This is the first study, to our knowledge, demonstrating the functional benefits and safety of dapagliflozin in symptomatic patients with sRV dysfunction under medical treatment with sacubitril/valsartan. These results support the need for larger randomized trials to further evaluate this therapeutic option in this population.

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Publication Details

Journal
Journal of the American Heart Association
Published
2025-05-29
DOI
https://doi.org/10.1161/jaha.124.040302
Citations
10
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
13.88
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article

Safety and Efficacy of Dapagliflozin in Patients With Systemic Right Ventricular Dysfunction: DAPA‐SRVTrial

Victor Waldmann, Laurence Iserin, Magalie Ladouceur, Ana Barat et al.
10 citations
Journal of the American Heart Association
Heart Failure Treatment and Management
13.88
article

Safety and Efficacy of Dapagliflozin in Patients With Systemic Right Ventricular Dysfunction: DAPA‐SRVTrial

Victor Waldmann, Laurence Iserin, Magalie Ladouceur, Ana Barat, Mathieu Albertini, Antoine Legendre, Anne‐Solene Chaussade, P. David
article en
10 citations

Abstract

This is the first study, to our knowledge, demonstrating the functional benefits and safety of dapagliflozin in symptomatic patients with sRV dysfunction under medical treatment with sacubitril/valsartan. These results support the need for larger randomized trials to further evaluate this therapeutic option in this population.

Journal of the American Heart AssociationVol. 14(11)
Inserm (FR), Université Paris Cité (FR), Hôpital Européen Georges-Pompidou (FR), University Hospital of Geneva (CH)
Good health and well-being
Openalex Percentile: Top 1%
Heart Failure Treatment and Management
13.88
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Safety and Efficacy of Dapagliflozin in Patients With Systemic Right Ventricular Dysfunction: DAPA‐SRVTrial — Victor Waldmann, Laurence Iserin, et al. · Journal of the American Heart Association (2025) | TGRS Research Map | TGRS