Metabolic Health Consequences of Switching to the Bictegravir/Emtricitabine/Tenofovir Alafenamide and Dolutegravir Plus Lamivudine Regimens in Virologically Suppressed People Living with HIV Aged > 40 Years: A Retrospective Real-World Study

In this study, the B/F/TAF or DTG/3TC regimens are safe for virologically suppressed PLWH aged > 40 years. The transition to B/F/TAF demonstrated dual clinical benefits, significantly reducing hyperglycemia incidence while preserving renal function.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-05-01
DOI
https://doi.org/10.2147/idr.s516775
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
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article

Metabolic Health Consequences of Switching to the Bictegravir/Emtricitabine/Tenofovir Alafenamide and Dolutegravir Plus Lamivudine Regimens in Virologically Suppressed People Living with HIV Aged > 40 Years: A Retrospective Real-World Study

Dingyan Yan, Wenhui Zhang, Feng Li, Jie Han et al.
1 links
Infection and Drug Resistance
HIV-related health complications and treatments
article

Metabolic Health Consequences of Switching to the Bictegravir/Emtricitabine/Tenofovir Alafenamide and Dolutegravir Plus Lamivudine Regimens in Virologically Suppressed People Living with HIV Aged > 40 Years: A Retrospective Real-World Study

Dingyan Yan, Wenhui Zhang, Feng Li, Jie Han, Jinchuan Shi, Rongrong Zheng, Zhongdong Zhang, Yi Wang
article en

Abstract

In this study, the B/F/TAF or DTG/3TC regimens are safe for virologically suppressed PLWH aged > 40 years. The transition to B/F/TAF demonstrated dual clinical benefits, significantly reducing hyperglycemia incidence while preserving renal function.

Infection and Drug ResistanceVol. Volume 18
Zhejiang Chinese Medical University (CN), Hangzhou Xixi hospital (CN)
Good health and well-being
Openalex Percentile: Top 80%
HIV-related health complications and treatments
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