Short Anagen Hair Syndrome and Its Association With <scp>WNT10A</scp> Gene Variants: A Report of Three Pediatric Cases
Short anagen hair syndrome (SAHS) is a rare hair disorder characterized by a shortened anagen phase, limiting hair growth to a few centimeters. SAHS is a benign condition often improving after puberty, with diagnosis supported by clinical, trichological, and genetic findings. We report three pediatric cases of persistently short hair, all with negative hair pull tests and trichogram findings revealing club-shaped roots, tapering, and hair shaft diameter variability. Genetic testing identified the c.682 T>A;p.(Phe228Ile) variant in heterozygosity in the WNT10A gene in two patients, a variant reported as a risk factor for the condition.
Authors
- Á. Hernández‐Martín (ORCID: https://orcid.org/0000-0001-7260-8718)
- Lucero Noguera‐Morel (ORCID: https://orcid.org/0000-0001-5694-8536)
- Nelly Marlene Román Mendoza (ORCID: https://orcid.org/0000-0003-4463-6249)
- Nelmar Valentina Ortiz‐Cabrera (ORCID: https://orcid.org/0000-0002-3835-7203)
- Barbara Fernández Garoz
- Sergio García‐González (ORCID: https://orcid.org/0009-0006-2628-092X)
- Magdalini Louka (ORCID: https://orcid.org/0009-0001-8460-8683)
Institutions
- Hospital Infantil Universitario Niño Jesús (ES)
Publication Details
- Journal
- Pediatric Dermatology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1111/pde.15976
- Primary Topic
- Hair Growth and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00