Direct Immunofluorescence (<scp>DIF</scp>) Microscopy of Skin Biopsies From Children: A Retrospective Cohort Study of 986 <scp>DIF</scp> Studies
The most frequent DIF pattern in children was that of IgA-predominant vasculitis. Pediatric DIF positivity rates closely mirrored those of adults, supporting similar biopsy thresholds. DIF results differed from the pretest impression in a substantial percentage, supporting the value of DIF in select situations in the pediatric population. After controlling for IgA vasculitis, biopsy site was not associated with DIF positivity.
Authors
- Heather D Hardway (ORCID: https://orcid.org/0000-0002-4246-4992)
- Jorge A. Rios‐Duarte (ORCID: https://orcid.org/0000-0002-0596-9158)
- Julia Scott Lehman (ORCID: https://orcid.org/0000-0002-7389-3853)
- Dawn Marie R. Davis (ORCID: https://orcid.org/0000-0001-6819-6044)
- Austin Todd
- Clint Christian T. Garbanzos
Institutions
- Mayo Clinic (US)
- Georgetown University (US)
- MedStar Georgetown University Hospital (US)
Publication Details
- Journal
- Pediatric Dermatology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1111/pde.15978
- Citations
- 1
- Primary Topic
- Autoimmune Bullous Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.47