TUBERCULOSIS-IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (TB-IRIS) IN AN HIV-POSITIVE PATIENT: A RARE CASE REPORT

Background: Tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is a paradoxical worsening of tuberculosis symptoms after initiation of antiretroviral therapy (ART) in HIV patients. Early identification is crucial for management.Case Presentation:We present the case of a 45-year-old male, Gulla Ram, recently diagnosed with HIV infection and pulmonary tuberculosis, who developed TB-IRIS two weeks after starting ART. Investigations and Management: Diagnosis was clinical, supported by laboratory and imaging findings. Management involved continuation of antitubercular therapy (ATT) and ART with the addition of corticosteroids.Conclusion:TB-IRIS remains an underdiagnosed and underreported complication in HIV-tuberculosis co-infection. Prompt recognition and appropriate therapy are essential to prevent morbidity