Impact of Tobacco Consumption on Salivary Protein Profiles: A MALDI-TOF Mass Spectrometry Study
Tobacco consumption significantly alters salivary protein profiles, promoting chronic inflammation, oxidative stress, and DNA repair dysregulation, all of which may contribute to oral carcinogenesis. These findings emphasize the utility of MALDI-TOF MS in detecting salivary biomarkers for early diagnosis of tobacco-related oral diseases and provide insights into the molecular pathways disrupted by tobacco use.
Authors
- S Sandhya
- Suganya Panneer Selvam (ORCID: https://orcid.org/0000-0002-9272-6444)
- S Manish
- Ramya Ramadoss (ORCID: https://orcid.org/0000-0001-9408-3158)
- K Hemashree (ORCID: https://orcid.org/0000-0001-9616-6539)
- Nitya Krishnasamy
Institutions
- Saveetha University (IN)
Publication Details
- Journal
- Asian Pacific Journal of Cancer Prevention
- Published
- 2025-05-01
- DOI
- https://doi.org/10.31557/apjcp.2025.26.5.1483
- Citations
- 2
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- Saveetha Dental College