Advancements in Minimally Invasive Surgery for Colorectal Cancer: A Paradigm Shift
Minimally invasive surgery (MIS) has revolutionized the treatment landscape for colorectal cancer, offering patients a range of options that prioritize precision, faster recovery, and improved functional outcomes.As surgical techniques continue to evolve, methods such as laparoscopic surgery, robotic-assisted surgery, transanal total mesorectal excision (TaTME), and natural orifice specimen extraction surgery (NOSES) are becoming increasingly integrated into clinical practice.This editorial explores these innovative techniques, their advantages, and the ongoing discussions surrounding their long-term effectiveness in terms of tumor prognosis, highlighting the paradigm shift that MIS represents in the management of colorectal cancer.Laparoscopic surgery has been foundational in minimally invasive approaches.Key studies have confirmed its safety and efficacy compared to traditional open surgery.For example, the MRC CLASICC trial found no significant differences in circumferential resection margin (CRM) positivity or complication rates between laparoscopic and open methods, although laparoscopic anterior rectal resection had a higher CRM positive rate.Long-term outcomes, including five-year overall survival (OS) and disease-free survival (DFS), showed no significant differences, suggesting laparoscopic techniques can achieve similar oncological results.However, debates persist regarding their long-term implications [1].The COLOR series [2] and COREAN [3] studies echoed these findings, noting benefits like reduced bleeding and faster recovery, while studies such as ALaCaRT [4] and ACOSOG Z6051 [5] raised concerns about CRM negative rates and mesorectal integrity, indicating that laparoscopic surgery may not always be non-inferior to open surgery.Robotic-assisted surgery offers significant advancements in treating ultra-low rectal cancer, addressing challenges posed by traditional laparoscopic techniques.It provides improved dexterity and visualization essential
Authors
- Samira Soleymani
- Hossein Neámatzadeh (ORCID: https://orcid.org/0000-0003-1031-9288)
- Ahmad Shirinzadeh-Dastgiri (ORCID: https://orcid.org/0009-0005-2152-5425)
- Amirhossein Rahmani (ORCID: https://orcid.org/0000-0002-1771-3053)
- Amirhosein Naseri (ORCID: https://orcid.org/0000-0001-8548-1330)
- Mehdi Khosravi-Mashizi
Institutions
- Iran University of Medical Sciences (IR)
- Shahid Sadoughi University of Medical Sciences and Health Services (IR)
- Aja University of Medical Sciences (IR)
- Iranshahr University (IR)
Publication Details
- Journal
- Asian Pacific Journal of Cancer Prevention
- Published
- 2025-05-01
- DOI
- https://doi.org/10.31557/apjcp.2025.26.5.1479
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00