Mathematical Modeling and Association Analysis Decipher the Impact of the Gut Microbiome on Cancer Immunotherapy
Integration of mathematical modeling and microbiome data reveals how gut microbiome components impact immune response, providing insights to optimize immunotherapy strategies. This article is part of a special series: Driving Cancer Discoveries with Computational Research, Data Science, and Machine Learning/AI.
Authors
- Lance L. Munn (ORCID: https://orcid.org/0000-0003-0698-7232)
- Andreas G. Hadjigeorgiou (ORCID: https://orcid.org/0000-0003-2484-0074)
- Rakesh K. Jain (ORCID: https://orcid.org/0000-0001-7571-3548)
- Nadim J. Ajami (ORCID: https://orcid.org/0000-0002-3808-8576)
- Jennifer Ann Wargo (ORCID: https://orcid.org/0000-0003-3438-7576)
- Aditya Kumar Mishra (ORCID: https://orcid.org/0000-0003-0775-3219)
- Golnaz Morad (ORCID: https://orcid.org/0000-0002-9460-618X)
- Triantafyllos Stylianopoulos (ORCID: https://orcid.org/0000-0002-3093-1696)
- Sarah B. Johnson (ORCID: https://orcid.org/0000-0001-8936-0958)
- Constantinos Harkos (ORCID: https://orcid.org/0000-0003-0261-1289)
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Harvard University (US)
- University of Cyprus (CY)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Cancer Research
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1158/0008-5472.can-24-2232
- Citations
- 3
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Sanofi
- European Commission
- Institut Gustave-Roussy
- Daiichi Sankyo Europe