Ex-vivo validation of nine algorithms for quantifying infarcts with late gadolinium enhancement cardiovascular magnetic resonance
EWA, Heiberg-08, FWHM, and FACT all perform on par with manual delineation, however, Heiberg-08, and FWHM are not suitable for phase sensitive inversion recovery images. The technique used to measure infarct size should be disclosed in clinical trials and in original research. Caution should be applied when comparing datasets employing different infarct quantification methods. Manual infarct delineation by experienced readers remains a reliable technique to measure infarct size.
Authors
- Sascha Kopic
- Håkan Arheden (ORCID: https://orcid.org/0000-0002-6124-3159)
- Dennis Nordlund (ORCID: https://orcid.org/0000-0001-9524-6908)
- Marcus Carlsson (ORCID: https://orcid.org/0000-0002-9480-5250)
- Einar Heiberg (ORCID: https://orcid.org/0000-0003-2848-3326)
- Robert Jablonowski (ORCID: https://orcid.org/0000-0001-9424-5663)
- Sebastian Bidhult (ORCID: https://orcid.org/0000-0001-8023-5026)
- Anthony H. Aletras (ORCID: https://orcid.org/0000-0002-3786-3817)
- Henrik Engblom (ORCID: https://orcid.org/0000-0001-6424-5646)
- Christos G. Xanthis (ORCID: https://orcid.org/0000-0003-1139-3658)
- Mikael Kanski (ORCID: https://orcid.org/0000-0002-2909-8510)
Institutions
- Lund University (SE)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Journal of Cardiovascular Magnetic Resonance
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.jocmr.2025.101915
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hjärt-Lungfonden
- Region Skåne