A Case of Erythrodermic Psoriasis Successfully Treated With Ixekizumab Combined With Low‐Dose Methotrexate to Ensure Sustained Clearance: A Case Report

Erythrodermic psoriasis (EP) is a severe type of psoriasis that requires immediate and effective treatment to prevent serious complications. Although recommended as first-line treatment for EP, conventional systemic disease-modifying antirheumatic drugs (csDMARDs) such as methotrexate and/or cyclosporine can sometimes be ineffective or undesirable, hence the use of biologics. However, in cases of refractory disease, biologics may be combined with methotrexate to boost efficacy and optimize outcomes without compromising safety and tolerability.

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Publication Details

Journal
Case Reports in Dermatological Medicine
Published
2025-01-01
DOI
https://doi.org/10.1155/crdm/8810497
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
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article

A Case of Erythrodermic Psoriasis Successfully Treated With Ixekizumab Combined With Low‐Dose Methotrexate to Ensure Sustained Clearance: A Case Report

Rogelio Balagat, Patricia Tinio, Jennifer Lavina Ngo, Lily Lyralin Tumalad
Case Reports in Dermatological Medicine
Psoriasis: Treatment and Pathogenesis
article

A Case of Erythrodermic Psoriasis Successfully Treated With Ixekizumab Combined With Low‐Dose Methotrexate to Ensure Sustained Clearance: A Case Report

Rogelio Balagat, Patricia Tinio, Jennifer Lavina Ngo, Lily Lyralin Tumalad
article en

Abstract

Erythrodermic psoriasis (EP) is a severe type of psoriasis that requires immediate and effective treatment to prevent serious complications. Although recommended as first-line treatment for EP, conventional systemic disease-modifying antirheumatic drugs (csDMARDs) such as methotrexate and/or cyclosporine can sometimes be ineffective or undesirable, hence the use of biologics. However, in cases of refractory disease, biologics may be combined with methotrexate to boost efficacy and optimize outcomes without compromising safety and tolerability.

Case Reports in Dermatological MedicineVol. 2025(1)
University of Asia and the Pacific (PH)
Openalex Percentile: Top 87%
Psoriasis: Treatment and Pathogenesis
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