Unraveling the Oncogenic Characteristics of the Cytolinker, Plectin, in Esophageal Squamous Cell Carcinoma
Plectin is involved in maintaining SSE homeostasis, and misexpression of plectin through its genetic alterations or transcriptional dysregulations perturbs the compositions, stoichiometries, and localizations of plectin, HD, DSM, and the cytoskeleton underlying the oncogenic characteristics of plectin.
Authors
- Xiaohong Yu (ORCID: https://orcid.org/0000-0003-2352-2023)
- Xiying Yu (ORCID: https://orcid.org/0000-0003-2779-9054)
- Wei Jiang (ORCID: https://orcid.org/0000-0002-2309-9571)
- Wei Zheng (ORCID: https://orcid.org/0000-0002-8942-1543)
- Ya‐Nan Yang (ORCID: https://orcid.org/0000-0001-6367-8431)
- Lei Xu (ORCID: https://orcid.org/0000-0002-4629-7415)
- Lili Qiao (ORCID: https://orcid.org/0000-0003-0359-3609)
- Hui Yuan (ORCID: https://orcid.org/0000-0003-2269-4034)
- Guodong Deng
- Yuanyuan Hu (ORCID: https://orcid.org/0000-0001-9019-6198)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.jcmgh.2025.101549
- Citations
- 1
- Primary Topic
- Skin and Cellular Biology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Natural Science Foundation of China
- Science and Technology Innovation 2025 Major Project of Ningbo
- Chinese Academy of Medical Sciences Initiative for Innovative Medicine