The clinical case of Fournier’s gangrene in a tuberculosis patient

Fournier’s gangrene (GF) is a specific form of necrotising fasciitis localised on the external genitalia as well as in the perianal region.The pathogenesis is based on arterial thrombosis leading to necrosis of the skin and subcutaneous fat, intoxication and multi-organ failure. The aim is to demonstrate a clinical case of HF, the background process for which was tuberculosis infection.We present a clinical case of a patient with fibrotic cavernous pulmonary tuberculosis treated in the tuberculosis extrapulmonary department of the Moscow Research and Clinical Center for Tuberculosis Control for advanced HF. Correctly selected complex treatment of HF consisting of wide dissection of necrotic tissues, adequate drainage, antibacterial and infusion therapy in combination with delayed corporoplasty with scrotal flaps prevented the development of a severe septic condition that could lead to death, and also preserved the patient’s quality of life. Conclusion . Mycobacterium tuberculosis may serve as both an etiological and predisposing factor in the development of HF (due to immunosuppression). Caution in relation to HF in patients with tuberculosis anamnesis, timely emergency care reduces the risk of fatal outcomes.

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Publication Details

Journal
Tuberkulez i socialʹno značimye zabolevaniâ
Published
2025-05-29
DOI
https://doi.org/10.54921/2413-0346-2025-13-1-79-83
Primary Topic
Streptococcal Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

The clinical case of Fournier’s gangrene in a tuberculosis patient

O. N. Zuban, M. P. Korchagin, М. А. Прокопович
Tuberkulez i socialʹno značimye zabolevaniâ
Streptococcal Infections and Treatments
article

The clinical case of Fournier’s gangrene in a tuberculosis patient

O. N. Zuban, M. P. Korchagin, М. А. Прокопович
article en

Abstract

Fournier’s gangrene (GF) is a specific form of necrotising fasciitis localised on the external genitalia as well as in the perianal region.The pathogenesis is based on arterial thrombosis leading to necrosis of the skin and subcutaneous fat, intoxication and multi-organ failure. The aim is to demonstrate a clinical case of HF, the background process for which was tuberculosis infection.We present a clinical case of a patient with fibrotic cavernous pulmonary tuberculosis treated in the tuberculosis extrapulmonary department of the Moscow Research and Clinical Center for Tuberculosis Control for advanced HF. Correctly selected complex treatment of HF consisting of wide dissection of necrotic tissues, adequate drainage, antibacterial and infusion therapy in combination with delayed corporoplasty with scrotal flaps prevented the development of a severe septic condition that could lead to death, and also preserved the patient’s quality of life. Conclusion . Mycobacterium tuberculosis may serve as both an etiological and predisposing factor in the development of HF (due to immunosuppression). Caution in relation to HF in patients with tuberculosis anamnesis, timely emergency care reduces the risk of fatal outcomes.

Tuberkulez i socialʹno značimye zabolevaniâVol. 13(1)
Russian Medical Academy of Continuous Professional Education (RU), Ministry of Health of the Russian Federation (RU)
Openalex Percentile: Top 83%
Streptococcal Infections and Treatments
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