Terahertz-Based Biosensor for Characterization of Cancerous Cells

This paper presents the development of a highly sensitive terahertz (THz) metamaterial biosensor designed for advanced biosensing applications, specifically for detecting cancerous cells. Utilizing THz-time domain spectroscopy (THzTDS), the sensor monitors variations in the refractive index and absorption characteristics of tissues, enabling the differentiation between normal and cancerous tissues. The biosensor is optimized through structural parameter adjustments to enhance sensitivity, achieving a remarkable 870 GHz per Refractive index unit (GHz/RIU) sensitivity. The optimized sensor’s high accuracy and reliability underscore its potential for early cancer detection, particularly for skin cancer. This study highlights the promise of THz biosensors in revolutionizing cancer diagnostics, offering a radiation-free, rapid, and sensitive solution for improved patient outcomes.