High-Fat Diet Differentially Regulates Fibroblast Growth Factor Expression in Metabolic Tissues of Young and Aged Male Mice
These findings underscore the tissue-specific dynamics of the FGF system under metabolic stress, identifying FGF1 as a promising therapeutic target for addressing obesity- and aging-related metabolic dysfunction.
Authors
- Lu Cai (ORCID: https://orcid.org/0000-0003-3048-1135)
- Yi Tan (ORCID: https://orcid.org/0000-0002-9798-6237)
- Xiaodan Hui
- Zhongbin Deng (ORCID: https://orcid.org/0000-0003-1409-5824)
- Wenqian Zhou (ORCID: https://orcid.org/0000-0002-1733-7123)
- Qian Lin
- Kyounghee Min (ORCID: https://orcid.org/0000-0002-2546-0236)
- Kupper A. Wintergerst
- Lijuan Xiong (ORCID: https://orcid.org/0000-0001-5643-4244)
- Sara E. Watson (ORCID: https://orcid.org/0000-0003-4316-1632)
- Jason Xu
- Chunjie Gu
Institutions
- University of Louisville (US)
- Kosair Children's Hospital (US)
- Rice Institute (US)
- Cardiovascular Innovation Institute (US)
- Norton Hospital (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Journal of the Endocrine Society
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1210/jendso/bvaf096
- Citations
- 1
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- American Diabetes Association
- University of Louisville
- National Institutes of Health