Dermoscopy-guided high-frequency ultrasound for preoperative assessment of basal cell carcinoma lateral margins: a pilot study
This study evaluated the diagnostic accuracy of dermoscopy-guided high-frequency ultrasound (DG-HFUS) for preoperative lateral margin assessment in basal cell carcinoma. DG-HFUS achieved 94.4% sensitivity and 93% specificity for detecting tumour presence within 2 mm of the margin, with strong correlation to histopathology. The results suggest that DG-HFUS is a promising noninvasive tool for surgical planning, especially where Mohs surgery is not available.
Authors
- Giovanni Pellacani (ORCID: https://orcid.org/0000-0002-7222-2951)
- Carmen Cantisani (ORCID: https://orcid.org/0000-0003-2181-951X)
- Kamran Avanaki (ORCID: https://orcid.org/0000-0002-1437-8456)
- Mariano Suppa (ORCID: https://orcid.org/0000-0002-9266-0342)
- András Bánvölgyi (ORCID: https://orcid.org/0000-0002-7071-1364)
- Mehdi Boostani (ORCID: https://orcid.org/0000-0001-9728-1117)
- Kende Lőrincz (ORCID: https://orcid.org/0000-0002-1861-1008)
- Norbert Kiss (ORCID: https://orcid.org/0000-0002-9947-1755)
- Ximena Wortsman (ORCID: https://orcid.org/0000-0003-3359-5023)
- Norbert Wikonkál (ORCID: https://orcid.org/0000-0003-4949-8711)
- Mohamad Goldust
- György Paragh (ORCID: https://orcid.org/0000-0002-6612-9267)
- Péter Holló (ORCID: https://orcid.org/0000-0002-0744-8989)
- Anita Mohos
- Paweł Pietkiewicz (ORCID: https://orcid.org/0000-0001-7262-2456)
Institutions
- Semmelweis University (HU)
- Roswell Park Comprehensive Cancer Center (US)
- Université Libre de Bruxelles (BE)
- University of Miami (US)
- Institut Jules Bordet (BE)
- Erasmus Hospital (BE)
- Yale University (US)
- University of Illinois Chicago (US)
- Vinci (United Kingdom) (GB)
- Central Military Hospital (NL)
- Leonardo (United Kingdom) (GB)
- Société Française de Cardiologie (FR)
- Leonardo Da Vinci University (PE)
- University of Chile (CL)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1093/bjd/ljaf209
- Citations
- 11
- Primary Topic
- Nonmelanoma Skin Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 14.90