Assessment of lung function and severity grading in interstitial lung diseases (% predicted versus z-scores) and association with survival: A retrospective cohort study of 6,808 patients
The recently recommended use of z-scores leads to significant reclassification of lung function results in patients with ILDs, largely driven by age. This approach is justified by its stronger prognostic associations. Severe TLCO impairment remains a robust predictor of mortality in ILDs.
Authors
- Magdalena Martusewicz-Boros (ORCID: https://orcid.org/0000-0002-7027-757X)
- Piotr Boros (ORCID: https://orcid.org/0000-0002-9153-8919)
- Katarzyna Lewandowska (ORCID: https://orcid.org/0000-0002-4648-2864)
Institutions
- Masih Daneshvari Hospital (IR)
- Lung Institute (US)
- National Center for Tuberculosis and Lung Disease (GE)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1371/journal.pmed.1004619
- Citations
- 3
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56