Convention Smears of Pleural Effusion Cytology Revealing Metastatic Clear Cell Carcinoma of Endometrium: A Rare Case Report and Review of Literature

Conventional fluid cytology is a simple and efficient diagnostic modality that plays an imperative role in the workup of serous cavity effusion fluids. Endometrial carcinoma with pleural metastases is quite uncommon, and isolated cases without lung parenchymal involvement are even more uncommon. Herein, we present a case of a 60-year-old female diagnosed with high-grade endometrioid carcinoma with clear cell change, who presented with right-sided pleural effusion, which turned out to be positive for metastatic carcinoma without the involvement of lung parenchyma, making it a rare presentation of endometrial carcinoma metastasis diagnosed on conventional fluid cytology.