DEVELOPMENT AND CHARECTARIZATION OF IXORA COCCINEA LINIMENT TO ALLEVIATE NOCICEPTIVE ACTIVITY

This research work is undertaken with the aim to formulate and evaluate Ixora coccinea liniment.Three different formulations were prepared and observed the physical characteristics like color, odor, and pH.The pH of the prepared formulations was found in between 5.24 to 5.54 which lies in normal pH range of the skin.The spectra of API and prepared formulations were determined by ATR-FTIR model.The particle size was also determined by microscopic method and the average particle size in the formulated liniment was 3.5 it concludes that final product is safe and compatible with excipients and also without causing any adverse effects.In-vitro drug release studies was performed and evaluated using Franz diffusion cell.From all the formulations F3 was concluded as optimized formulation as it showed higher drug release.