CONCEPTUAL UNDERSTANDING OF MYASTHENIA GRAVIS ON THE BASIS OF VYANVAYU AND OTHER VYADHI GHATAK

In Myasthenia gravis is a disease, where AChRs in the neuromuscular junction are destroyed by immune bodies which develop due to an autoimmune disease [1].Treatment is use anticholine esterase drugs and immunosuppressive drugs (to suppress the immune bodies which destroy the AChRs).Myasthenia gravis has prevalence as high 200 in 100,000.It affects individuals in all age groups, but peak incidences occur in women in their twenties and thirties and in men in their fifties and sixties.Overall, women are affected more frequently than men, in a ratio of 3:2.In MG, the fundamental defect is a decrease in the number of available AChRs at the postsynaptic muscle membrane.It presents with fluctuating skeletal muscle weakness and fatigue most commonly affecting the ocular muscles, although any muscle may be affected.Ayurvedic therapies can give much more promising results.Comparison between myasthenia gravis and diseases explained in Ayurveda is difficult and exact correlation is not possible.But based on critical understanding of prakrut karma of vyan vayu and its vikrut karma and also included other vyadhighataka, a probable diagnosis can be made and treated accordingly.