Bidirectional genetic links between chronic obstructive pulmonary disease and frailty: Genome-wide association study insights
Our study shows a common genetic foundation for COPD and frailty, identifying multiple shared loci and offering insights into their underlying causal connections. These findings enhance our understanding of the biological mechanisms linking these conditions and may guide future research and treatment strategies for related diseases.
Authors
- Tong Tong Wu (ORCID: https://orcid.org/0000-0002-1175-9923)
- Qiang Meng (ORCID: https://orcid.org/0000-0002-0132-0001)
- Feng Qu (ORCID: https://orcid.org/0009-0008-6043-7665)
- Fuhui Yan (ORCID: https://orcid.org/0009-0004-8672-2350)
Institutions
- Affiliated Hospital of Hangzhou Normal University (CN)
- Jining First People's Hospital (CN)
- Shandong First Medical University (CN)
- Jining Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1371/journal.pone.0320304
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00