Clinical Implementation of Expanded Solid Tumor Fusion Detection With Whole-Transcriptome Sequencing at an Academic Cancer Center
WTS provides high sensitivity, specificity, and expanded fusion detection, supporting its routine clinical adoption. Future work will explore its broader role in integrated genomic profiling and therapeutic guidance.
Authors
- Gregory J. Tsongalis (ORCID: https://orcid.org/0000-0002-0792-3196)
- Jeremiah Karrs (ORCID: https://orcid.org/0000-0002-5064-159X)
- Drew T. Bergman (ORCID: https://orcid.org/0000-0002-8314-7088)
- Joel A. Lefferts (ORCID: https://orcid.org/0000-0002-5083-7867)
- Laura J. Tafe (ORCID: https://orcid.org/0000-0001-9613-641X)
- Nevena B. Ognjenovic
- Edward G. Hughes
- Donald C. Green
- Shrey Sukhadia (ORCID: https://orcid.org/0009-0009-1168-1060)
- Jennifer N. Barbuto
- Parth Shah (ORCID: https://orcid.org/0000-0003-0726-0764)
- RAJEEV VYAS
- Brianna E. Palisoul
- Zofia Cieslak
Institutions
- Dartmouth College (US)
- Dartmouth–Hitchcock Medical Center (US)
Publication Details
- Journal
- JCO Precision Oncology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1200/po-24-00830
- Citations
- 2
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.87