Comparison of the frequency of viral infections in patients with inborn errors of immunity receiving immunoglobulin by different routes

• This study reveals key insights into viral infections in PID patients receiving immunoglobulin replacement therapy (IRT) during winter. The overall viral infection rate was 3.79%, with IVIG at 4.2%, cSCIG at 2.5%, and fSCIG at 4.4%. Notably, the cSCIG group had a significantly lower infection rate than the IVIG and fSCIG groups (p0.05). These findings suggest that cSCIG may lower the risk of viral infections in PID patients during high-risk winter months.