Safety and efficacy of sirolimus combined with cyclosporine in primary membranous nephropathy: a randomized controlled trial
Sirolimus combined with cyclosporine was noninferior to cyclosporine monotherapy in achieving clinical remission in MN and demonstrated superior benefits in immunological remission and kidney function preservation.
Authors
- Chao Yang (ORCID: https://orcid.org/0000-0001-8732-5497)
- Yi-Miao Zhang
- Yao Yao (ORCID: https://orcid.org/0000-0002-0879-4269)
- Liqiang Meng (ORCID: https://orcid.org/0000-0003-3897-3054)
- Zhao Cui (ORCID: https://orcid.org/0000-0002-5837-1926)
- Fang Wang (ORCID: https://orcid.org/0000-0002-4781-8673)
- Gang Liu (ORCID: https://orcid.org/0000-0002-5995-2634)
- Ting Li (ORCID: https://orcid.org/0000-0001-5145-3024)
- Xin Wang (ORCID: https://orcid.org/0000-0002-7296-9406)
- Yue Shu
- Ming‐Hui Zhao
- Caixia Lin
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Peking University First Hospital (CN)
- Ministry of Health (TT)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s12916-025-04173-0
- Citations
- 1
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Peking University First Hospital
- National Natural Science Foundation of China
- Peking University