Functional medicine approaches to energy metabolism: chronic fatigue syndrome, brain-gut axis and weight control

Chronic fatigue syndrome is a long-term condition that can affect different parts of the body which includes symptoms of extreme tiredness which can make daily activities difficult, sleep problems, brain fog. The symptom “chronic fatigue” might seem like a simple physical status; however, it might be a crucial sign of mitochondria dysfunction, problematic neurotransmitter synthesis, increased micro-inflammation and/or increased gut permeability. These metabolic conditions are likely to cause lethal vascular diseases, neurological deficits, psychological disorders or serious immune reactions if patients do not receive proper care. Thorough clinical approaches and individualized treatments should be achieved not only to resolve symptoms but also to maintain healthy status. Functional medicine approach from simple blood analysis to urine organic acid analysis and food IgG4 antibody test and treatment methods which help to recover mitochondrial function could be proper options.

Authors

Publication Details

Journal
Korean Institute for Functional Medicine
Published
2025-05-30
DOI
https://doi.org/10.32581/jkifm.2025.8.1.103
Primary Topic
Diet and metabolism studies
Type
article
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article

Functional medicine approaches to energy metabolism: chronic fatigue syndrome, brain-gut axis and weight control

Sung-Weon Jung, Kyungsun Han
1 links
Korean Institute for Functional Medicine
Diet and metabolism studies
article

Functional medicine approaches to energy metabolism: chronic fatigue syndrome, brain-gut axis and weight control

Sung-Weon Jung, Kyungsun Han
article en

Abstract

Chronic fatigue syndrome is a long-term condition that can affect different parts of the body which includes symptoms of extreme tiredness which can make daily activities difficult, sleep problems, brain fog. The symptom “chronic fatigue” might seem like a simple physical status; however, it might be a crucial sign of mitochondria dysfunction, problematic neurotransmitter synthesis, increased micro-inflammation and/or increased gut permeability. These metabolic conditions are likely to cause lethal vascular diseases, neurological deficits, psychological disorders or serious immune reactions if patients do not receive proper care. Thorough clinical approaches and individualized treatments should be achieved not only to resolve symptoms but also to maintain healthy status. Functional medicine approach from simple blood analysis to urine organic acid analysis and food IgG4 antibody test and treatment methods which help to recover mitochondrial function could be proper options.

Korean Institute for Functional MedicineVol. 8(1)
Openalex Percentile: Top 84%
Diet and metabolism studies
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