Exploring the pathways linking fasting insulin to coronary artery disease: a proteome-wide Mendelian randomization study
This study identified five protein mediators linking insulin to CAD. These proteins could be considered as potential targets to mitigate insulin-related cardiovascular risk, providing novel insights for drug repurposing.
Authors
- Jie Zhao (ORCID: https://orcid.org/0000-0002-1564-0057)
- Xin Huang (ORCID: https://orcid.org/0000-0001-5213-7664)
Institutions
- University of Hong Kong (HK)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s12916-025-04127-6
- Citations
- 5
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 9.09