[Proportions of memory T cells and expression of their associated cytokines in lymph nodes of mice infected with <i>Echinococcus multilocularis</i>].

Tm cells levels are consistently increased in lymph nodes of mice at different stages of <i>E. multilocularis</i> infection, with Trm cells as the predominantly elevated subset. The impaired capacity of CD8<sup>+</sup> Tm cells to secrete the effector molecule TNF-α in mouse lymph nodes at the late-stage infection may facilitate chronic parasitism of <i>E. multilocularis</i>.

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Publication Details

Journal
PubMed
Published
2025-05-09
DOI
https://doi.org/10.16250/j.32.1915.2024224
Primary Topic
Immunotoxicology and immune responses
Type
article
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article

[Proportions of memory T cells and expression of their associated cytokines in lymph nodes of mice infected with Echinococcus multilocularis].

Shengzhi Sun, Bin Deng, Abidan Ainiwaer, C Zhang et al.
PubMed
Immunotoxicology and immune responses
article

[Proportions of memory T cells and expression of their associated cytokines in lymph nodes of mice infected with Echinococcus multilocularis].

Shengzhi Sun, Bin Deng, Abidan Ainiwaer, C Zhang, Na Tang, Weidong Xiao, Chutian Ge, Tao Jiang, D Adilai, Jing Li, Heng Wang, Yubin Li
article en

Abstract

Tm cells levels are consistently increased in lymph nodes of mice at different stages of <i>E. multilocularis</i> infection, with Trm cells as the predominantly elevated subset. The impaired capacity of CD8<sup>+</sup> Tm cells to secrete the effector molecule TNF-α in mouse lymph nodes at the late-stage infection may facilitate chronic parasitism of <i>E. multilocularis</i>.

PubMedVol. 37(2)
Xinjiang Medical University (CN), First Affiliated Hospital of Xinjiang Medical University (CN), Xinjiang Uygur Autonomous Region Education Department (CN)
Good health and well-being
Immunotoxicology and immune responses
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[Proportions of memory T cells and expression of their associated cytokines in lymph nodes of mice infected with <i>Echinococcus multilocularis</i>]. — Shengzhi Sun, Bin Deng, et al. · PubMed (2025) | TGRS Research Map | TGRS