[Recurrent thrombosis despite oral anticoagulation? A case report].

We describe a 34-year-old female patient with recurrent thromboembolic events, most recently with occlusion of the superior mesenteric vein - despite regular intake of oral anticoagulation with Apixaban at the dosage recommended by the manufacturer. The underlying cause was enteral malabsorption with protein loss syndrome due to active Crohn's disease, limited to the small intestine, with an atypical clinical presentation. We discuss the topic of anticoagulation in the presence of an enteral barrier disorder.

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Publication Details

Journal
PubMed
Published
2025-05-01
DOI
https://doi.org/10.23785/praxis.2025.05.008
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
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article

[Recurrent thrombosis despite oral anticoagulation? A case report].

Florian Prenner, Sigute Silingaite
PubMed
Venous Thromboembolism Diagnosis and Management
article

[Recurrent thrombosis despite oral anticoagulation? A case report].

Florian Prenner, Sigute Silingaite
article en

Abstract

We describe a 34-year-old female patient with recurrent thromboembolic events, most recently with occlusion of the superior mesenteric vein - despite regular intake of oral anticoagulation with Apixaban at the dosage recommended by the manufacturer. The underlying cause was enteral malabsorption with protein loss syndrome due to active Crohn's disease, limited to the small intestine, with an atypical clinical presentation. We discuss the topic of anticoagulation in the presence of an enteral barrier disorder.

PubMedVol. 114(5)
University Hospital of Zurich (CH)
Openalex Percentile: Top 75%
Venous Thromboembolism Diagnosis and Management
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[Recurrent thrombosis despite oral anticoagulation? A case report]. — Florian Prenner, Sigute Silingaite · PubMed (2025) | TGRS Research Map | TGRS