Dietary Intake Changes in Healthy Adults Following a Well-Formulated Ketogenic Diet

data from 3-day diet records collected within the parent study.An interim analysis was done using R version 4.3.1.Generalized estimating equations (GEE) modeling was used to estimate population-averaged effects, focusing on overall trends across the population, accounting for within-individual correlation occurring in repeated measures.Results: The parent study will be completed in January 2025.We expect to analyze data from 18 participants; an interim analysis of data from 4 participants is presented here.The participants were 47.8AE15.3years, had a body mass index of 32.5 AE 4.4 kg/m 2 , and were 75% female, and 100% White.During the intervention, higher changes in body weight from baseline were predicted by higher energy intake ( estimate 0.03, standard error 0.01, P 0.002).Females had lower body weight compared to males ( estimate -33.75, standard error 10.79, P 0.002).Only 1 of the 4 participants changed body weight by > 5% from baseline.Changes in dietary intake of macronutrients were not associated with changes in body weight (P > 0.05).Conclusions: The interim analysis for an ongoing clinical trial will provide information on weight stability and correlates of weight changes among study participants.